Objective To investigate the feasibility and safety of narcotrend during painless bronchoscopy, and to monitor the depth of anesthesia. Methods Sixty hospitalized patients that undertook painless bronchoscopy were divided randomly into two groups, with all of them undertook propofol combined with sufentanil total intravenous anesthesia. Group A was the experience group and group B was NT group. The depth of anesthesia was controlled by anaesthetist according to his experience in group A; the depth of anesthesia was controlled by anaesthetist according to NT value in group B. The NT stage was maintained at D1E0.NT index was maintained at 27~56. Vital sigh of specific time points, anesthetic and cardiovascular active drugs amount, operation and recovery time, the incidence of intraoperative and postoperative adverse reaction were recorded respectively, The effects of anesthesia were evaluated by physicians specialized in respiratory. Results The differences in heart rate and blood pressure between the two groups were not significant. At specific time point during anesthesia the oxygen saturation in group A was significantly lower than that in group B (P<0.05). The consumption of propofol in group A was significantly more than that in group B, the recovery time in group A was significantly longer than that in group B (P<0.05). There was no statistically significant difference in the two groups of patients in the amount of sufentanil and cardiovascular active drugs, operation time, as well as the incidence of postoperative nausea and vomiting, intraoperative awareness. The patients had more cough and body movement in group A than that in group B, and the difference was statistically significant (P<0.05). The effects of anesthesia in group A were generally better than that in group B (P<0.05). Conclusion Anesthesia depth monitoring with narcotrend in painless bronchoscopy using total intravenous propofol combined with sufentanil, can reduce hypoxemia incidence and the amount of propofol, shorten the recovery time, and improve the satisfaction of intraoperative anesthetic effect.%目的 在无痛纤支镜检查中使用Narcotrend (NT)监测麻醉深度,探讨其可行性及安全性.方法 60例行无痛纤支镜检查的住院患者,随机并平均被分成A、B两组,均接受丙泊酚复合舒芬太尼全凭静脉麻醉,其中A组为经验组,B组为NT组.A组患者接受麻醉医师根据经验调控麻醉深度；B组患者接受麻醉医师根据NT值调控麻醉深度,以维持NT分级在D1～E0,NTI值为27～56,分别记录两组患者设定时间点的生命体征、麻醉及心血管活性药物用量、操作及苏醒时间、术中术后不良反应发生率,并由呼吸科医生对麻醉效果做出评价.结果 两组患者相对应时段的心率、血压差异无统计学意义(P＞0.05),麻醉后两对应时间点A组血氧饱和度较B组低(P＜0.05),A组患者丙泊酚用量明显较B组多,苏醒时间明显较B组长(P＜0.05),两组患者舒芬太尼用量、心血管活性药物用量、操作时间、术后恶心呕吐发生发生率、术中知晓等情况差异均无统计学意义(P＞0.05),A组发生体动呛咳较B组多(P＜0.05),两组患者麻醉效果B组明显优于A组(P＜0.05).结论 Narcotrend在无痛纤支镜检查中对丙泊酚复合舒芬太尼全凭静脉麻醉深度进行监测,能降低低氧血症发生率,减少丙泊酚物用量,缩短患者清醒时间,提高术者对麻醉效果的满意度.
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