Objective To investigate the clinical effect of submucosal epinephrine injection combined with loop electrosurgical excision procedure (LEEP) of polypectomy and titanium clip enclosed polyp residual in treatment of patients with digestive polyps, and provide reference for the clinical diagnosis and treatment of digestive polyps. Methods A total of 100 patients with digestive polyps, who admitted to Department of Gastroenterology of Pingchang County People's Hospital from January 2016 to June 2016, were selected and divided into the control group and observa-tion group according to random number table, with 50 cases in each group. The control group was given LEEP therapy, and the observation group was given submucosal epinephrine injection combined with LEEP of polypectomy and titani-um clip enclosed polyp residual therapy. The surgical time, intraoperative blood loss, first meal time, intraoperative, post-operative complications, polyp recurrence rate of 6 months and 12 months after surgery in the two groups were observed and compared. Results The intraoperative blood loss of the observation group was (5.0 ± 4.1) mL, which was lower than (8.1±4.7) mL in the control group (P<0.05), but there was no statistically significant difference between the two groups in surgical time and first meal time (P>0.05). The complications of the observation group was 8.0%, which was significantly lower than 24.0% of the control group (P<0.05). The bleeding rate of the observation group was 0, which was significantly lower than 12.0% of the control group (P<0.05). The polyp recurrence rates of 6 months after surgery in the control group and the observation group were respectively 8.0% and 4.0%, there were no statistically significant difference between the two groups (P>0.05). The polyp recurrence rates of 12 months after surgery in the control group was 16.0% versus 4.0% in the observation group (P<0.05). Conclusion The therapy of submucosal epinephrine injec-tion combined with LEEP of polypectomy and titanium clip enclosed polyp residual has confirmed clinical effect in the treatment of patients with digestive polyps, which can help to reduce bleeding and long-term recurrence rate.%目的 探讨黏膜下注射肾上腺素联合高频电刀息肉切除、息肉残端钛夹夹闭治疗消化道息肉的临床疗效,为消化道息肉的治疗提供参考.方法 选取2016年1~6月期间平昌县人民医院消化内科收治的100例消化道息肉患者,采用随机数表法将患者分为对照组和观察组,每组50例.对照组采用单纯高频电刀息肉切除术,观察组采用黏膜下注射肾上腺素联合高频电刀息肉切除、息肉残端钛夹夹闭治疗.比较两组患者的手术时间、术中出血量、术后首次进餐时间、术中及术后并发症,以及术后6个月及12个月时息肉复发情况.结果 观察组患者的术中出血量为(5.0±4.1) mL,少于对照组的(8.1±4.7) mL,差异有统计学意义(P<0.05),但手术时间和术后首次进餐时间两组比较差异均无统计学意义(P>0.05);观察组患者的术后并发症发生率为8.0%,明显低于对照组的24.0%,差异有统计学意义(P<0.05),其中出血发生率对照组为12.0%,观察组为0,差异有统计学意义(P<0.05);术后6个月时,对照组与观察组患者的息肉复发率分别为8.0%、4.0%,差异无统计学意义(P>0.05),而12个月时,息肉复发率观察组为4.0%,明显低于对照组的16.0%,差异有统计学意义(P<0.05).结论 黏膜下注射肾上腺素联合高频电刀息肉切除、息肉残端钛夹夹闭治疗消化道息肉疗效肯定,有助于减少出血,降低息肉远期复发率.
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