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HPV与宫颈癌发生的关联及意义

         

摘要

目的 探讨女性生殖道感染人乳头瘤病毒(HPV)与宫颈癌发生的关系,分析其临床意义。方法本次研究选择的对象共320例,均为2000年1月至2012年10月来我院就诊的妇女患者,使用HPV分型基因检测系统对其宫颈细胞的HPV DNA进行检测,并且检测20种高危型HPV亚型和5种低危型亚型。结果人乳头瘤病毒阳性率20.5%,其中高危型HPV亚型15.75%,低危型亚型3.02%,高危亚型和低危亚型混合型1.23%。HPV11是低危型中感染最高的,HPV16是高危型中感染最高的。结论女性生殖道感染人乳头瘤病毒(HPV)易引发宫颈癌,临床上应做好提前防范,及早预防,防止发生癌变。%Objective To explore the human papilloma virus infection in the female reproductive tract ( HPV ) and cervical cancer, to analyze its clinical significance. Methods this study,of 320 cases were in 2000, January-2012 year in October in our hospital were women, the use of HPV genotyping system of the cervical cells of HPV DNA were detected, and the detection of 20 kinds of high-risk HPV subtypes and 5 low-risk subtypes. Results The positive rate of HPV 20.5%, wherein the high-risk HPV subtypes 15.75%, low-risk subtypes 3.02%, high-risk subtypes and low-risk subtype 1.23%mixed type. HPV11 is a low-risk types of HPV16 is the highest, high risk of infection with the highest. Conclusion Human papilloma virus infection in female genital tract ( HPV ) can lead to cervical cancer, clinical should do the early prevention, early prevention, prevent the occurrence of cancer.

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