两种途径的新辅助化疗在宫颈癌治疗中的疗效观察

摘要

Objective Comparing two different pathways neoadjuvant chemotherapy clinical efficacy in the treatment of locally advanced cervical cancer. Methods 52 patients with locally advanced cervical cancer patients were randomly divided into: 24 cases, NAIT (artery intervention chemotherapy) group, 28 cases, NVCT (intravenous chemotherapy) group. The two groups were compared chemotherapy efficiency, the risk of relapse rate and adverse reactions. Results There were no significant difference in effective rate between two groups (P>0.05). Parametrial invasion, vascular invasion and adverse reactions incidence the NAIT group was significantly lower than NVCT group (P<0.05). Conclusion There would be effective, small risk recurrence to treat patients of locally advanced cervix cancer by neoadjuvant chemotherapy with artery intervention%　　目的比较两种不同途径的新辅助化疗在局部晚期宫颈癌治疗中的临床疗效。方法对52例局部晚期宫颈癌患者进行新辅助化疗，随机分成：NAIT(动脉介入化疗)组24例，NVCT(静脉化疗)组28例。比较两组化疗有效率、复发风险率及不良反应。结果两组化疗有效率比较,差异无统计学意义(P ＞0.05)；宫旁浸润、脉管浸润及不良反应的发生率 NAIT 组明显低于 NVCT 组(P ＜0.05)；结论动脉介入途径新辅助化疗治疗局部晚期宫颈癌临床疗效好，复发风险小，是一种安全有效的给药途径。