234例青少年小主动脉瓣环主动脉瓣病变外科手术效果的临床分析

摘要

Objective To explore the clinical analysis of surgical operation effect of adolescent small aortic annulus aortic valve disease, and to guide clinical practice and clinical effect. Methods In our hospital in small aortic annulus aortic valve disease in adolescent patients with 234 cases, were randomly divided into two groups with 117 cases in each group, to observe the application of aortic valve replacement and annulus enlargement, including 25 cases of Nicks, 36 cases of Konno, 56 cases in group C were treated by Ross, the control group received traditional operation therapy, echocardiography evaluation of cardiac function after operation, two groups to improve the situation and the operation parameter index. Results The patients were followed up for 1-3 years, left ventricular mass index, observation group, posterior wall thickness, the aortic transvalvular pressure difference were significantly better than control group(P<0.05);improve heart function class NYHA has two groups after treatment, but NYHA cardiac function grade observation group improved more significantly than the control group(P<0.05). Conclusion Aortic valve replacement and mitral annular dilation operation, can effectively improve the success rate of operation, rapid postoperative recovery, promote growth, improve the quality of life of patients, increase the survival rate, clinical effect, is worth the clinical promotion.%目的：探讨青少年小主动脉瓣环主动脉瓣病变的外科手术效果临床分析，以指导临床实践及临床疗效。方法入选我院小主动脉瓣环主动脉瓣病变青少年患者234例，随机分为两组各117例，观察组应用主动脉瓣置换术同时行瓣环扩大术，其中25例行Nicks法，36例行Konno法，C组56例行Ross法，对照组进行施行传统单纯换瓣膜手术疗法（主动脉瓣环不扩大），术后复查心脏彩超，评估两组的心功能改善情况及各手术参数指标情况。结果术后随访1~3年，观察组的左室质量指数、左室后壁厚度、主动脉跨瓣压差等情况均显著优于对照组（P<0.05）；治疗后两组的心功能NYHA等级均有改善，但观察组的心功能NYHA等级改善情况显著优于对照组（P<0.05）。结论主动脉瓣置换术同时行瓣环扩大手术，可有效提高手术成功率，术后恢复快，促进生长发育，改善患者生活质量，提高远期生存率，临床效果确切，值得临床推广。