阴道镜下宫颈活检与LEEP术后病理检查对宫颈上皮内瘤变的诊断价值

摘要

目的：通过比较宫颈上皮内瘤变（CIN）术前阴道镜下宫颈活检与宫颈环形电切除术（LEEP）后病理检查结果的差异，评价二者在宫颈上皮内瘤变的诊断价值及其准确性。方法对2013年1月至2013年12月209例疑似CIN在我院行阴道镜下宫颈活检和LEEP手术以及术后病理组织检查进行对照比较。阴道镜宫颈活检病理结果其中炎症7例，CINI 52例，CINⅡ72例，CINⅢ53例，均行LEEP手术。结果209例均行LEEP手术，阴道镜下活组织病理检查结果与LEEP术后病理检查手术结果完全符合率为55.50%，诊断过度率27.75%，诊断不足率17.70%，漏诊宫颈浸润癌0.96%。结论阴道镜下宫颈活检与LEEP术病理检查均是有效诊断宫颈上皮内瘤变的方法，但二者联合可提高诊断准确性。%Objective To investigate the differences of patholog ical results between colposcopic cervical biopsy and loop electrosurgical excision procedure(LEEP), and to eva luate the value in the diagnosis of cervical intraepithelial neoplasia(CIN) and its accuracy.Methods On January 2013 to December 2013, 209 cases of suspected CIN in our line of cervical biopsy under colposcope and LEEP operation and postoperative histopathologic examination were compared. Colposcopy cervical biopsy pathology results 7 cases of inflammation, 52 cases of CINI, 72 cases of CINⅡ, 53 cases of CINⅢ, all cases were performed LEEP operation.Results 209 cases were performed LEEP surgery and biopsy under colposcope pathologic examination results and the LEEP postoperative pathologic examination results completely coincidence rate was 55.50%, operation excessive diagnosis rate was 27.75%, the diagnostic rate of less than 17.70%, the misdiagnosis and cervical invasive cancer by 0.96%.Conclusion Cervical biopsy under colposcope and LEEP pathological examination are effective method of diagnosis of cervical intraepithelial neoplasia, but both can improve the diagnostic accuracy.