首页> 中文期刊> 《中国医药指南》 >D-二聚体、C反应蛋白、降钙素原水平与老年社区获得性肺炎严重程度及预后的关系

D-二聚体、C反应蛋白、降钙素原水平与老年社区获得性肺炎严重程度及预后的关系

         

摘要

目的:探讨D-二聚体、C反应蛋白、降钙素原水平与老年社区获得性肺炎严重程度及预后的关系。方法选取社区获得性肺炎的患者90例,参照肺炎严重指数,将患者分为低危组(肺炎严重指数积分<90分)、中危组(肺炎严重指数积分91~130分)、高危组(肺炎严重指数积分>130分)。分析对比低危组、中危组、高危组D-二聚体、C反应蛋白、降钙素原水平。按照社区获得性肺炎的疾病进展,进一步将90例患者分为死亡组和存活组,对比两组间D-二聚体、C反应蛋白、降钙素原水平。结果低危组、中危组、高危组的D-二聚体、C反应蛋白、降钙素原水平结果比较有差异(P<0.05)。预后存活的社区获得性肺炎者与预后死亡的社区获得性肺炎者的D-二聚体、C反应蛋白、降钙素原水平结果比较有差异(P<0.05)。结论本次研究认为D-二聚体、C反应蛋白、降钙素原水平与老年社区获得性肺炎的严重程度有一定关系,可评价预后。%Objective To discuss the relationship between D-dimer, C-reactive protein, procalcitonin levels and the severity and prognosis of elderly community-acquired pneumonia. Methods 90 cases of community-acquired pneumonia were selected. According to pneumonia severity index score, they were divided into low-danger group (score<90), medium-danger group (91-130) and high-danger group (>130). According to disease progress, the cases were again divided into death group and survival group. D-dimer, C-reactive protein and procalcitonin levels of these groups were compared respectively. Results D-dimer, C-reactive protein and procalcitonin levels of low-danger group, medium-danger group and high-danger group were significantly different (P<0.05), and those of death group and survival group were also significantly different (P<0.05). Conclusion The study suggested there was a certain relationship between D-dimer, C-reactive protein, procalcitonin levels and elderly community-acquired pneumonia.

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