中药离子导入配合穴位按摩对儿童弱视的图形视觉诱发电位的影响

摘要

Objective To observe the efficacy of Chinese herbs iontophoresis plus eye point massage on the change of pattern visual evoked potential P-VEP ) in amblyopia children. Methods One hundred and seventeen amblyopia patients( 198 eyes ) were randomly divided into control group with 58 patients( 97 eyes:79 eyes with ametropic amblyopia ,4 eyes with strabismic amblyopia, 14 eyes with anisometropic amblyopia ) and Chinese herbs iontophoresis treatment group with 59 patients( 101 eyes:84 eyes with ametropic amblyopia,5 eyes with strabismic amblyopia, 12 eyes with anisometropic amblyopia ). The control group was given eyeglasses after mydriatic optometry with 1% atropine and treated with occlusion therapy and eyesight exercise. The treatment group was given self-made Chinese herbs( pericarpium citri reticulatae viride, Semen Cassiae, chrysanthemum, borneol, Olibanum, Spearmint, the fruit of Chinese wolfberry, flowers carthami, Angelica sinensis,butterflybush flower,the root of red-rooted salvia,the seed of Chinese dodder,prepared rehmannia root ) iontophoresis plus eye point massage besides the methods mentioned above. Both groups were treated continually for 6 months. Results Before treatment, three types of amblyopia showed no significant difference in the PI 00 wave amplitude ( P100-A ) and latencyv P100-L ) of P-VEP between two groups( P >0. 05 ). After treatment, the increase of P100-A in treatment group was significantly higher than that in control group( P <0.05 ),but P100-L shortened significantly compared with the controls( P <0.05 ). Conclusion Chinese herbs iontophoresis plus eye point massage for amblyopia children can make P-VEP-P100 wave latency shortened and amplitude increased, and it is an effective method for the treatment of amblyopia.%目的 观察中药离子导入配合眼周穴位按摩对儿童的图形视觉诱发电位(P-VEP)的影响.方法 弱视儿童117例(198只眼)按随机数字表法分为对照组58例(97只眼,其中屈光不正性弱视79眼,斜视性弱视4眼,屈光参差性弱视14眼)和中药组59例(101只眼,其中屈光不正性弱视84眼,斜视性弱视5眼,屈光参差性弱视12眼).对照组用1%阿托品滴眼液点眼后验光配镜,同时采用遮盖方法 及精细作业治疗.中药组在对照组治疗方法 的基础上采用自拟中药方(青皮、决明子、菊花、冰片、乳香、薄荷、枸杞子、红花、当归、密蒙花、丹参、菟丝子、熟地黄)离子导入并按摩眼部穴位.治疗6个月.结果 治疗前两组3种类型弱视P-VEP、P100波的波幅(P100-L)和潜伏期(P100-A)比较,差异无统计学意义(P＞0.05);治疗后中药组P100-A增加幅度较对照组高(P＜0.05),P100-L较对照组明显缩短(P＜0.05).结论 中药离子导入配合按摩眼部穴位治疗儿童弱视能使P-VEP的P100波潜伏期缩短,振幅增高,是治疗弱视的一种有效方法.