目的 探讨试食不同血糖负荷(GL)早餐对2型糖尿病患者餐后血糖和C肽的影响,为GL概念在糖尿病营养宣教和饮食干预中的应用提供理论依据.方法 将74例2型糖尿病受试者随机分为A、B两组,每组37例.给予A组混合餐a (GL33.6);给予B组混合餐b(GL43.0).从A组中随机抽取14例受试者构成C组,使其分别再于不同的两日分别试食混合餐c (GL34.6)和混合餐d(GL54.2).观察受试者空腹和餐后2h血糖、C肽的变化情况,并运用统计学软件SPSS19.0数据包对数据进行分析处理.结果 A组的餐后2h血糖低于B组,差异具有统计学意义；比较试食3种不同混合餐后C组指标后发现试食d餐后的2hPG和2hC-P低于试食a餐和c餐,差异具有统计学意义；试食a餐与c餐后此两者无统计学差异.结论 低GL饮食对糖尿病患者餐后血糖的控制具有一定作用,应考虑将其进一步推广于糖尿病的营养宣教和饮食干预中.%Objective To study the effects of different glycemic load breakfast on postprandial blood glucose and C peptide of patients with type 2 diabetes mellitus in order to provide basis for the application of glycemic load to nutrition propagation and diet therapy. Methods 74 patients with type 2 diabetes mellitus were randomly divided into Group A and B, 37 cases each group. Cases in the Group A were supported with Set a (GL33.6), while cases in the Group B were supported with Set b (GL44.0). In addition, 14 cases (Group C) from Group A were respectively received Set c (GL34.6) and Set d (GL54.2) on two other days. The serum levels of glucose and C-peptide were measured at 0 min and 2 hours after meal. SPSS 19.0 software bag was used to analyze the data. Results 2 hours postprandial blood glucose (2 h PG) of Group A was significantly lower than that of Group B. As for the 14 cases of Group C, there were statistic differences after eating three sets. The levels of 2 h PG and 2 h C-peptide were significantly lower after eating Set d, compared with after eating Set a or Set c. No statistic difference was observed after eating Set a and Set c. Conclusion Low glycemic load diet can help to control the blood glucose response, which should be taken more use for the MNT of diabetes and the nutrition propagation of healthy ones.
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