Improving sorghum's disease resistance is one of the major objectives in our breeding program, as it is essential for the crop's high yield and desirable quality. In recent years, the advancement in molecular biotechnology fueled the significant progress in sorghum genome research. A large number of the critical resistance genes in sorghum have now been added on the genetic linkage map. It helps propel the studies on the physiology, resistance mechanism, resistance gene cloning, molecular marker assisted selection, favorable gene directed transfer and gene pyramiding on sorghum. In this article, notable achievements, such as the mapping of the QTL that resists drought and genes that resists diseases, pests, parasitic grasses or low temperatures, are summarized; the scientific challenges and anticipated future developments in the field of study are discussed; and specifically, some potential applications of the resistant gene mapping for sorghum breeding are presented.%抗病性是高粱遗传改良的主要目标,是高粱高产、优质的重要保证.近年来,随着分子生物技术的进步,高粱基因组研究得到迅速发展,大量重要的抗性性状基因被定位于相应的高粱遗传连锁图上,这为高粱抗性机制的生理研究、抗性基因的克隆、分子标记辅助选择、有利基因的定向转移及基因聚合奠定了基础.本文综述了高粱抗旱性QTL、抗病性基因、抗虫性基因、抗寄生草及耐寒性基因定位的研究进展,探讨抗性基因定位存在的问题及其有效利用,展望了高粱抗性基因定位在高粱遗传育种研究中的应用前景.
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