“代谢记忆”与糖尿病肾病

摘要

高血糖“代谢记忆”现象是指糖尿病患者由于早期高血糖作用,即使后期采取有效措施将血糖控制在正常水平,仍易发生糖尿病相关的并发症.糖尿病肾病是一种常见的糖尿病微血管并发症,是患者发生终末期肾脏病的主要原因,本文主要就“代谢记忆”与糖尿病肾病发生发展的关系进行综述.%Metabolic memory is a phenomenon that the diabetic complications continue to develop and progress in individuals who exposed a period of high glucose in the early stage and then returned to normal blood glucose after effective control.Diabetic nephropathy (DN) is one of the common diabetic microangiopathy and the main cause of end stage renal disease (ESRD).This review mainly summarizes the relationships between metabolic memory and the development of DN.