静脉药物配置中心的运行效果探讨Δ

摘要

OBJECTIVE:To discuss the initial development and effects of pharmacy intravenous admixture services (PIVAS) in Dongguan the First People ’s Hospital(hereinafter referred to as “our hospital”), so as to provide reference for the development of PIVAS , improve clinical pharmacists ’pharmaceutical care and to further enhance the clinical medication safety .METHODS:The configuration time of intravenous drug , number of drug store , deficiencies of drug quality management , number of infusion reactions , number of irrational prescriptions and allocation cost of intravenous drug in Jan.to Dec.2014(before PIVAS) and Jan.to Dec.2015 (after PIVAS) were statistically analyzed.And changes were compared after putting PIVAS into operation over one year , respectively .RESULTS: After PIVAS, the average configuration time of intravenous drug was ( 11.42 ±9.52 ) d, significantly shorter than that of before PIVAS [ (17.62 ±0.71 ) d ] , with extremely statistically significant difference ( P <0.01 ) .The fraction defective of storage conditions of drugs was 6.67%, the unstandard rate of validity of management was 13.33%, both of which were significantly lower than that of before PIVAS (17.31%and 23.07%), with statistically significant difference (P<0.05). There were 107 cases of infusion reactions , decreased by 30.51%compared with 154 cases before PIVAS .The irrational rate of prescriptions was 4.55%(164/3 600), significantly lower than that of before PIVAS [7.97%(287/3 600)], with extremely statistically significant difference ( P <0.01 ) . The total allocation cost of intravenous drug in 6 main departments decreased significantly compared with before PIVAS , with statistically significant difference ( P <0.05 ) . CONCLUSIONS:PIVAS has obvious advantages compared with the traditional infusion configuration mode , but there are some problems which remain to be resolved and improved in the preliminary operation .%目的：探讨东莞市第五人民医院（以下简称“我院”）静脉药物配置中心（ pharmacy intravenous admixture services ，PIVAS）初步运行效果，为PIVAS的发展提供参考，完善药师用药干预措施，进一步提高临床用药安全性。方法：统计我院科室静脉药物配置时间、储存药品的品种数及药品质量管理缺陷、输液反应例数、不合理处方数、静脉药物配置成本等数据，比较其在PIVAS运行前后的变化。结果：PIVAS运行后，科室平均静脉药物配置时间为（11．42±9．52） d，明显短于运行前的（17．62±0．71） d，差异有极显著统计学意义（ P＜0．01）；药品储存条件不合格率为6．67％、效期管理不规范率为13．33％，均明显低于运行前的17．31％、23．07％，差异均有统计学意义（ P＜0．05）；发生输液反应107例，较运行前的154例降低30．51％；处方不合理率为4．55％（164／3600），明显于极显著运行前的7．97％（287／3600），差异有极显著统计学意义（P＜0．01）；6个主要科室静脉药物2014年1—12月（ PIVAS运行前）与2015年1—12月（ PIVAS运行后）配置合计成本较运行前明显降低，差异有统计学意义（ P＜0．05）。结论：PIVAS较传统静脉药物配置模式具有明显优势，但在初步运行过程中尚存在若干问题，仍需不断改进和完善。