OBJECTIVE:To probe into the anesthetic effect of dezocine combined with propofol in painless induced abortion. METHODS: 90 patients who were prepared to painless artificial abortion admitted into Xiaogan Maternal and Child Health Hospital from Aug. 2016 to Feb. 2017 were selected and divided into observation group and control group via random number table, with 45 cases in each group. The control group was narcotized with remifentanil combined with propofol, while the observation group was given dezocine combined with propofol. The anesthetic effect, operation duration, dosage of propofol, recovery time of orientation, awaking time, 10 min postoperative pain score, post-anesthesia oxyhemoglobin saturation, and different times of systolic blood pressure ( SBP) , diastolic blood pressure ( DBP ) and heart rate, incidence of adverse drug reactions of two groups was observed. RESULTS: The total effective rate of anesthesia in the observation group was 95. 56％ ( 43/45 ) , significantly higher than that in the control group [ 82. 22％( 37/45 ) ]; the dosage of propofol, operation duration, recovery time of orientation, awaking time and the post-anesthesia oxyhemoglobin saturation of observation group was (95. 51 ± 6. 61 ) mg, ( 5. 51 ± 1. 41 ) min, ( 4. 62 ± 1. 21 ) min, ( 4. 51 ± 1. 61 ) min and ( 98. 51 ± 2. 61 )％, significantly better than those of the control group[(113. 39 ± 12. 57) mg,(7. 39 ± 2. 77) min,(6. 61 ± 2. 59) min, (7. 39 ± 2. 57) min and (93. 39 ± 1. 57)％], with statistically significant differences(P<0. 05). At 5 min after the operation started and 5 min post-operation, the DBP, SBP and heart rate of two groups were higher slightly than those before the operation, but the indicators of observation group were significantly lower than those of the control group, with statistically significant differences( P<0. 05 ) . The incidence of adverse drug reactions of observation group was significantly lower than that of the control group, with statistically significant difference(P<0. 05). CONCLUSIONS:The anesthetic effect of dezocine combined with propofol in painless induced abortion is remarkable, which can maintain the stability of vital signs and help to relieve pain, the decrease of dosage of propofol can shorten the operation duration and postoperative recovery time, with higher safety.%目的:探讨地佐辛联合丙泊酚用于无痛人工流产术的麻醉效果.方法:选取2016年8月—2017年2月孝感市妇幼保健院收治的拟行无痛人工流产术患者90例,以随机数字表法分为观察组和对照组各45例.对照组患者给予瑞芬太尼联合丙泊酚麻醉,观察组患者给予地佐辛联合丙泊酚麻醉.对比观察两组患者的麻醉效果、无痛人工流产术时间、丙泊酚用量、恢复定向力时间、清醒时间、术后10 min疼痛评分、麻醉后血氧饱和度及治疗不同时间的收缩压、舒张压、心率及不良反应发生情况.结果:观察组患者麻醉总有效率为95.56％(43/45),明显高于对照组的82.22％(37/45);观察组患者丙泊酚用量、无痛人工流产术时间、恢复定向力时间、清醒时间及麻醉后的血氧饱和度分别为(95.51±6.61)mg、(5.51±1.41)min、(4.62±1.21)min、(4.51±1.61)min及(98.51±2.61)％,明显优于对照组的(113.39±12.57)mg、(7.39±2.77)min、(6.61±2.59)min、(7.39±2.57)min及(93.39±1.57)％,差异均有统计学意义(P<0.05).手术开始5 min、术后5 min,两组患者舒张压、收缩压和心率较术前有所升高,但观察组患者各指标明显低于对照组,差异均有统计学意义(P<0.05).观察组患者不良反应发生率明显低于对照组,差异有统计学意义(P<0.05).结论:地佐辛联合丙泊酚用于无痛人工流产术的麻醉效果较好,可维持患者术中生命体征稳定,减轻患者痛苦,减少丙泊酚用量,缩短手术时间和术后麻醉恢复时间,安全性较高.
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