七氟烷与氯胺酮分别用于儿童手术全身麻醉的对比研究

摘要

OBJECTIVE:To probe into the effects of sevoflurane and ketamine in children with general anesthesia . METHODS:123 children undergoing surgical anesthesia admitted into Hanchuan People's Hospital from Oct .2015 to Oct.2016 were selected to be divided into observation group and control group via the random number table , with 61 cases in observation group and 62 cases in control group .The observation group were treated with sevoflurane mask inhalation anesthesia induction , while the control group received ketamine intravenous anesthesia .The anesthesia condition and adverse drug reactions of two groups were observed and compared after operation .RESULTS: The induction time , recovery time and extubation time in observation group were significantly shorter than those in control group, and the incidence of adverse drug reactions after operation were significantly lower than that in control group , with statistical significance ( P <0.05 ) . CONCLUSIONS: For children with general anesthesia , the effects of sevoflurane anesthesia induction is better than the ketamine anesthesia induction .%目的：探讨七氟烷与氯胺酮分别用于儿童手术全身麻醉的效果。方法：选取2015年10月—2016年10月汉川市人民医院收治的需进行手术麻醉的患儿123例作为研究对象。以随机数字表法将患儿分为观察组61例和对照组62例。观察组患儿给予七氟烷面罩吸入麻醉诱导，对照组患儿给予氯胺酮静脉注射麻醉。观察2组患儿麻醉情况及术后不良反应发生情况。结果：观察组患儿的诱导时间、意识恢复时间及拔管时间均明显短于对照组，且不良反应发生率明显低于对照组，差异均有统计学意义（P＜0.05）。结论：采用七氟烷麻醉诱导用于儿童手术全身麻醉的效果明显优于氯胺酮。