Cervical cancer is one of the common malignant tumours in gynecology. So far, its global occurrence rate is the highest among malignancies of female's reproductive system and the death rate is the second highest. Glaucoma is a blinding condition which is characterized by pathological intraocular hypertension, or damage of optic disc and retinal nerve fibre layer, and glaucomatous visual change under normal intraocular pressure. Typical clinical manifestations are sudden rise of intraocular pressure along with headache, nausea, vomiting, halo vision, eye distension and blurred vision. Two main types of glaucoma are open-angle and angle-closure glaucoma. Primary acute angle-closure glaucoma is one of the emergencies in ophthalmology and is caused by the sudden rise of the intraocular pressure secondary to the difficulty of aqueous humor drainage from angle closure. Without timely treatments, the risk of blindness is extremely high. For the severe case, it can cause total blindness within a few days. Inappropriate treatments can also influence treatment effectiveness. It is worthwhile to investigate the causes of these two concurrent diseases which are hardly related. In this article, we report two cases where acute angle-closure glaucoma developed after the radical surgery of cervical cancer with general anesthesia. We discuss the possible causes with respect to gene, anatomical and physiological factors, psychological factors, and preoperative narcotics, aiming to serve as clinical reference.
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