如何抓住新诊断2型糖尿病患者治疗的“黄金时间”

摘要

As a chronic progressive disease, type 2 diabetes melitus with the duration extension, islet beta cel function failure gradualy, and increased blood sugar. Early intensive treatment can eliminate sugar toxicity by quickly and significantly improve the function of islet beta cels, some patients get long-term blood sugar. Therefore, we should start as early as possible for the treatment to reverse a further deterioration in islet beta cel function. Bowel to promote pancreatic hormone as an important target for type 2 diabetes treatment. DPP - 4 inhibitors provide endogenous glp-1 effective concentrations, west Glenn dean as the first listed DPP - 4 inhibitors, and al kinds of oral medications and insulin combination, can further improve glycaemic control.%2型糖尿病作为慢性进展性疾病，随着病程延长，胰岛β细胞功能逐渐衰竭，而加剧血糖恶化。早期强化治疗能通过快速消除糖毒性，显著改善胰岛β细胞功能，使部分患者获得长期血糖缓解，因而，应尽早开始治疗以遏制胰岛β细胞功能的进一步恶化。肠促胰素作为2型糖尿病治疗的重要靶点，DPP-4抑制剂有效提供内源性GLP-1浓度，西格列汀作为第一个上市的DPP-4抑制剂，与各种口服降糖药及胰岛素联用，均能进一步改善患者的血糖控制。