Objective:To explore therapeutic effect and adverse reaction of three different dosages of morphine in treatment of pain, to improve the quality of life of patients. Methods:75 cases of patients in our hospital were randomly divided into group A pain oral and intravenous drug group B and group C subcutaneous drug group (25 cases in each group). 24h after treatment, three sets of pain relief effectiveness, ease the pain of working time and the best time and adverse reactions were compared. Results:In terms of pain relief effectiveness and adverse reactions, three groups had no statistical difference;intravenous injection can quickly and effectively alleviate pain, oral medicine is obviously better than the effect of group and the subcutaneous drug group. Conclusion:For pain relief, intravenous morphine can quickly and effectively alleviate patients' pain, thus it is worth clinical promotion.%目的：探究吗啡的三种不同给药方式在治疗癌痛中的治疗效果和不良反应，提高患者的生存质量。方法：将我院收治的75例癌痛患者随机分为A组口服给药、B组静脉给药和C组皮下给药组，每组25例。治疗24h后，比较三组疼痛缓解有效率、疼痛得到缓解的起效时间和最佳时间及不良反应。结果：在疼痛缓解有效率和不良反应方面，三组均无统计学差异；在疼痛得到缓解的起效时间和最佳时间方面，静脉注射能快速且有效缓解疼痛，效果明显优于口服给药组和皮下给药组。结论：对癌痛的缓解，静脉注射吗啡效果较好，能快速且有效缓解患者疼痛，值得在临床中推广。
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