LEEP刀治疗对中重度宫颈糜烂患者炎性因子与宫颈微循环状态的影响研究

摘要

目的：观察LEEP刀治疗对中重度宫颈糜烂患者炎性因子与宫颈微循环状态的影响。方法选取2012年1月-2013年3月进行治疗的70例中重度宫颈糜烂患者为研究对象，将其随机分为对照组与观察组，各35例，对照组进行常规微波治疗。观察组则以LEEP刀进行治疗。将两组患者治疗前后的血清炎性因子（IL-6和IL-8）与宫颈微循环检测指标进行比较。结果治疗后3 d观察组血清IL-6和IL-8含量分别为（10.10±1.28）pg/mL和（10.41±1.49）pg/mL，阳性率分别为34.29%和28.57%，均低于对照组（均P＜0.05），治疗后观察组宫颈部位红细胞聚集中重度比例为14.29%，低于对照组（P＜0.05）。结论 LEEP刀治疗对中重度宫颈糜烂患者炎性因子与宫颈微循环状态的影响更为积极，治疗作用更为明显。%Objective To observe the influence of LEEP knife for the inflammatory and cervical microcirculation state of patients with moderate and severe cervical erosion.Methods Seventy patients with moderate and severe cervical erosion in our hospital from January 2012 to March 2013 were selected as research object,and they were randomly divided into control group 35 cases and observation groupwith 35 cases in each group,the control group were treated with microwave ,the observation group were treated with LEEP knife,then the serum inflammatory factors and cervical microcirculation indexes of two groups before and at third day after the treatment were compared. Results After treatment of 3 days,content of serum IL-6 and IL 8 levels in observation group were(10.10±1.28)pg/mL and(10.41±1.49)pg/mL,positive rates were 34.29%and 28.57%,they were all lower than the control group, (all P<0.05), ratio of cervical part erythrocyte aggregation relation in the observation group was 14.29%,and it was lower than that in the control group (P<0.05). Conclusion The influence of LEEP knife for the inflammatory and cervical microcirculation state of patients with moderate and severe cervical erosion is more active,so its treatment role is more obvious.