急诊抢救重症哮喘合并呼吸衰竭218例临床效果分析

摘要

Objective To observe and analyze the emergency department with severe asthma and respiratory failure clinical effects. Methods Our hospital from April 2007 to April 2012 218 cases of patients with severe asthma with respiratory failure, divided into observation group and control group, each with 109 cases in the control group taking conventional treatment, the observation group in the control group on the basis of mechanical ventilation adjuvant therapy were observed in both groups in treatment effect. Results After treatment, 4 h, heart rate (HR), respiratory frequency (RR), PaCO 2, PaO 2 before treatment comparison are obviously improved, more obvious improvement of the observation group (P<0.05), with statistical signiifcance. The the observation group long-term use of theophylline proportion of drugs, regular use of corticosteroid hormones proportion intermittent use of inhaled β2 agonists proportion, mortality was significantly lower than the control group (P<0.05), with statistical signiifcance. Conclusion The conventional treatment with mechanical ventilation auxiliary emergency rescue severe asthma with respiratory failure clinical efifcacy signiifcantly relieve asthma attacks and reduce mortality, to save the lives of patients has important clinical value.%　　目的探讨急诊抢救重症哮喘合并呼吸衰竭的临床效果。方法选取梅州市人民医院2007年4月-2012年4月收治的218例重症哮喘合并呼吸衰竭患者为研究对象，随机分为观察组与对照组，每组各109例，对照组采取常规治疗，观察组在对照组基础上给予机械通气辅助治疗，观察对比两组治疗效果。结果两组治疗后4 h的心率（HR）、呼吸频率（RR）、PaCO 2、PaO2与治疗前比较皆有明显改善，观察组改善程度更为明显（P＜0.05），差异具有统计学意义。观察组长期使用茶碱类药物比例、规律使用皮质类激素比例、间断应用吸入β2激动剂比例、病死率显著低于对照组（P＜0.05），差异具有统计学意义。结论常规治疗联合机械通气辅助急诊抢救重症哮喘合并呼吸衰竭临床疗效显著，缓解哮喘发作，降低病死率，最大限度地抢救患者生命，具有重要的临床应用价值。