24例早期子宫内膜癌临床病理分析

摘要

探讨早期子宫内膜癌的临床病理特点、治疗方法及预后。方法回顾分析洛阳北方企业集团有限公司职工医院2003年1月～2013年9月收治的Ⅰ期子宫内膜癌的24例临床资料，术前经诊刮确诊子宫内膜癌或重度不典型增生，术前影像学检查未发现盆腔肿大淋巴结及子宫以外的其他部位的淋巴结转移。结果23例患者行全子宫及双侧附件切除术，其中4例行盆腔淋巴结清扫术，1例未做手术行孕激素治疗，24例患者经随访0～10年,未见术后复发及转移。结论单纯全子宫+双附件切除术是治疗早期子宫内膜腺癌(ⅠA期和ⅠB期)的最佳治疗方案。对于有生育要求的年轻女性,也可以考虑保守治疗,应用大剂量的孕激素治疗,但应加强临床与病理沟通,密切随访。%Objective To investigate the clinicopathologic features of early stage Endometrial cancer , the method of treatment for this disease and its prognosis.Methods The clinical date of 24 cases of stage of stageⅠendometrial carcinoma treated in Hospital Of Luo Yang Northen Enterprise Goup, between January 2003and September 2013 were retrospectively analyzed, All of patientds were pathologicaly diagnosed for endometral cancer or severe dysplasia by properative curettage.medical imagelogy didn't detect metastasis in the abdominal or pelric lymph nodes or masses outside the uterus.Results 23 patients received regular hysterectomy, bilateral salpingo-oophorectomy. 4 cases among these patients received pelvic lymph node dissetion. One patient received progestins treatment without surgery. 24 cases were followed up between zero to ten years. There are no recurrences and metastasis.Conclusion For patients with early stage (ⅠA-ⅠB) endometrial adenocarcinoma,regular hysterectomy and bilateral salpingo-oophorectomy is an optimal tyeatment, as for yong women with fertility deman. It is good conservative therapy for high dose progesterone, hower, it strenthen clinical and pathology cooperation and follow up for these patients.