新鲜冰冻血浆不合理输注的原因分析

摘要

Objective Analysis of the infusion of fresh frozen plasma (FFP) unreasonable reason, reduce the unreasonable FFP infusion. Methods Longgang district of shenzhen ping to people's hospital were retrospectively analyzed in 493 cases of medical records of infusion FFP, infusion purposes;Infusion of reasonable and unreasonable infusion group within the infusion infusion of FFP before and after 8 h prothrombin time (PT) and activated partial blood clotting enzyme time (APTT) test results. Results The ratio of reasonable FFP transfusion was 63.61%(314/439), and the ratio of unreasonable FFP transfusion was 36.31%(179/439). The result had statistical significance which PT and APTT between before blood transfusion and 8 h after blood transfusion in reasonable FFP transfusion (P<0.05). The result had no statistical significance which PT and APTT between before blood transfusion and 8 h after blood transfusion in unreasonable FFP transfusion. Conclusion To supplement protein, expansion and increase nutrition for purpose is the main cause of the FFP infusion is not reasonable. Not a lot of bleeding or clotting function was abnormal and even infusion FFP can not improve the function of blood coagulation. In order to promote the ascension of clinical blood transfusion safety, save the limited resources of blood, the need to strengthen the clinical transfusion management of FFP.%目的：分析新鲜冰冻血浆(FFP)的不合理输注原因，减少FFP不合理输注。方法回顾性分析深圳市龙岗区坪地人民医院493例输注FFP的病历资料，输注目的；比较合理输注组和不合理输注组在输注FFP前及输注后8 h内凝血酶原时间(PT)及活化部分凝血活酶时间(APTT)的检查结果。结果输注FFP患者中，合理输注者为63.61%(314/439)，不合理输注者为36.31%(179/439)；合理组PT、APTT值输注后明显低于输注前，差异有统计学意义(P<0.05)，不合理组输注前、后PT、APTT值比较，两者差异无统计学意义。结论以补充蛋白、扩容及增加营养者为目的是导致FFP输注不合理的最主要原因。非大量出血或凝血功能异常者即使输注FFP也不会改善凝血功能。为促进临床输血安全性的提升，节约有限的血液资源，需要临床上加强FFP的输血管理。