心房颤动环肺静脉消融术后早期复发预测因素的临床分析

摘要

Objective To investigate the forecast factors of early recurrence of Atrial fibrillation (ERAF)after circumferential pulmonary vein ablation (CPVA). Method 120 patients with paroxysmal atrial fibrillation who underwent CPVA from January 2010 to October 2013 in the hospital were stdied. All patients were divided into recurrence group (40 cases) and non-recurrence group (80 cases) according to hether postoperative relapse. The predictors of ERAF after CPVA were explored. Results Univariate analysis showed that high blood pressure, P wave dispersion, Left atrial diameter, preoperative and postoperative NT-proBNP levels , AF duration were property closely associated with recurrence (P<0.05);Multivariate analysis showed that P wave dispersion and preoperative NT-proBNP were the predictor of recurrence. Conclusion P wave dispersion and preoperative NT-proBNP is a predictor of ERAF after CPVA, P wave dispersion improved ability to predict recurrence and improve preoperative NT-proBNP is prompted increased susceptibility to atrial fibrillation, can predict postoperative relapse.%目的：探讨心房颤动（AF）环肺静脉消融术(CPVA)后早期复发预测因素。方法收集2010年1月～2013年10月江苏省徐州市中心医院收治的阵发性AF患者120例，实施CPVA进行治疗，根据术后是否复发分为复发组（38例）和未复发组（82例），探讨术后早期复发的预测因素。结果经单因素分析显示，高血压、P波离散度、左心房内径、术前及术后NT-proBNP水平以及AF持续时间均与术后复发密切相关（P<0.05）；经多因素分析显示，P波离散度以及术前NT-proBNP是术后复发的预测因素。结论 P波离散度以及术前NT-proBNP是CPVA术后复发的预测因素，P波离散度提高能够预测复发，而术前NT-proBNP提高则提示AF易感性增强，亦可预测术后复发。