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BIO MARKER FOR PREDICTING EARLY-RELAPSE AFTER OPERATION FOR LUNG ADENOCARCINOMA

机译:预测肺腺癌手术后早期复发的生物标志物

摘要

PURPOSE: A biomarker for predicting initial recurrence after lung adenocarcinoma surgery by observing mutation of gene on a specific site is provided. CONSTITUTION: A biomarker for predicting initial recurrence after lung adenocarcinoma surgery contains chromosome sites 5q21.3, 7p11.2, 9q34.11, 10p11.22, 11p13, 11p15.1, 11p15.4, 12p13.31, 16p13.12, 16q22.1, 17q11.2 or 21q22.11 or nucleic acid sequence thereof. A method for predicting initial reoccurrence after lung adenocarcinoma surgery comprises: a step of extracting nucleic acids from cancer tissue or cancer cells; a step of hybridizing the nucleic acids with nucleic acids which selectively bind to the biomarker; and a step of detecting hybridization complex.
机译:目的:提供一种生物标志物,通过观察特定部位的基因突变来预测肺腺癌手术后的初始复发。组成:用于预测肺腺癌手术后初始复发的生物标记物包含染色体位点5q21.3、7p11.2、9q34.11、10p11.22、11p13、11p15.1、11p15.4、12p13.31、16p13.12、16q22 .1、17q11.2或21q22.11或其核酸序列。一种预测肺腺癌手术后复发的方法,包括:从癌组织或癌细胞中提取核酸的步骤;使核酸与选择性结合生物标志物的核酸杂交的步骤;以及检测杂交复合物的步骤。

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