目的：对血液中微粒及血小板减少的临床检验进行分析和探讨。方法选取100例急性白血病化疗后、急性脑梗死、冠心病患者作为试验组，选取同期健康体检者100例作为对照组，比较2组患者的血小板微粒释放情况。结果经过检测，试验组中急性脑梗死血小板微粒量(6.6×105±3.2×105)/mL、冠心病患者的血小板微粒量(6.3×105±2.4×105)/mL显著多于对照组(1.4×105±5.3×105)/mL，活化后的血小板微粒释放量(1.8×105±7.5×105)/mL显著多于静息状态下血小板微粒释放量(1.4×105±5.3×105)/mL，差异均具有统计学意义（P<0.05）。结论在血栓类疾病的诊断中，对患者血小板微粒的检测可以作为明确的检测指标，同时血小板微粒检测对血小板活化也有重要意义，值得在临床上进行广泛应用。%Objective To analyze and discuss particles in the blood and the clinical test of thrombocytopenia. Methods 100 cases of acute leukemia after chemotherapy, patients with acute cerebral infarction, coronary heart disease were selected as the experimental group. 100 cases of healthy check-up during the same period were selected as the control group. To compare two groups of patients with platelet particle release. Results After testing, the test group of patients with acute cerebral infarction (6.6×105±3.2×105)/mL, coronary heart disease in platelet amount of particles (6.3×105±2.4×105)/mL were signiifcantly more than the control group (1.4×105±5.3×105)/mL. Activation of platelet particles released after (1.8×105±7.5×105)/mL was signiifcantly more than the resting state of platelet particles to release a quantity (1.4×105±5.3×105)/mL (P<0.05). Conclusion In diagnosis of thrombosis diseases, to detect patients with platelet particles can be used as a speciifc detection index, at the same time the platelet particles detection also has important signiifcance for platelet activation, it is worth of widely used in clinic.
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