目的：比较罗哌卡因和布比卡因在腰硬联合麻醉中应用的临床效果。方法将进行腰硬联合麻醉的100例患者随机分为试验组和对照组，各50例。试验组应用罗哌卡因进行腰硬联合麻醉，对照组应用布比卡因进行腰硬联合麻醉。比较2组患者的感觉状况及运动阻滞起效时间、感觉阻滞消退的时间以及各组患者感觉阻滞最高平面和不良反应发生率等。同时，对患者麻醉后的血压变化情况进行比较。结果试验组患者麻醉的优良率为88.0%，而对照组患者的优良率为92.0%，2组患者麻醉效果差异无统计学意义；试验组患者运动阻滞起效时间为（170.0±41.2）s，对照组为（169.3±43.6）s，2组比较差异无统计学意义（t=0.5363，P>0.05）；试验组患者感觉阻滞起效时间分别（52.0±9.9）s；对照组为（50.0±10.0）s，2组比较差异无统计学意义；试验组患者不良反应发生率为10.0%，对照组患者不良反应发生率为24.0%，试验组患者不良反应发生率明显低于对照组（P<0.05)。结论在腰硬联合麻醉中应用罗哌卡因不仅临床效果显著，而且对患者体循环系统影响小。%Objective To compare the clinical effects of the application of ropivacaine and bupivacaine in CSEA. Methods 100 patients were randomly divided into experimental group(50 patients) and control group(50 patients). Experimental group used ropivacaine combined spinal epidural anesthesia , control group used bupivacaine combined spinal epidural anesthesia. Feeling status and motor block onset time, sensory regression of time, and each group of patients the highest sensory block plane and probability of adverse reactions occur and so on in two groups were compared. Meanwhile, changes in blood pressure in patients after anesthesia were compared. Results Compared with control group, feeling, motor block onset time and block level aspects in the experimental group had no signiifcant difference compared with control group;adverse reactions in anesthesia in experimental group was lower than the control group;Meanwhile, the vital signs of patients in the experimental group did not change, while the control group were signiifcantly lower blood pressure. Conclusion Application of combined spinal-epidural anesthesia with ropivacaine is only signiifcant clinical effect, but also for patients with circulation system is small.
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