探讨影响萍乡地区胆石病临床流行病学的相关因素

摘要

Objective To investigate the factors influencing the investigation and clinical epidemiology of gallstone disease Pingxiang region. Methods Selected 2253 cases of gallstone patients as research subjects, patient medical records were retrospectively analyzed and summarized the development of clinical epidemiology of gallstone disease conditions according to medicalrecords case-by tablesfilled out the application SPSS13.0 statistical analysis, statistical analysis of the relationship between the relevant factors as gender, age, diet, occupation and gallstone disease.Results Medical records of 2,253 cases of gallstone disease outcome, including gallstones 1937 cases (85.97%), extrahepatic bile duct stones in 261 cases (11.58%), 55 cases of intrahepatic bile duct stones (2.45%). Women than men, the total proportion of 1:1.74, sex and site of gallstone disease in each group had no significant difference. 51 - 60 and 41 - 50two blocks for the peak age of onset of gallstone disease, and up to 51.04% in both groups, the difference was significant (P <0.05). Diet in patients with gallstone up 86.9 percent fat diet, a low diet in patients with intrahepatic bile duct stones in the proportion of high-fat diet, which is about 1.02%, mainly concentrated in the diet protein diet (17.2%) and carbohydrates (27.4%); extrahepatic bile duct stones in patients with diet protein diet larger proportion, up 37.5 percent. Farmers the highest incidence (38.6%), followed by staff (35.9%). Conclusion The main types of gallstone disease in the region of gallbladder stones, mainly concentrated in the age of onset between 40-60 years of age, a close associate of sex, diet and the incidence of occupational and gallstone disease exists.%目的 调查和探讨影响萍乡地区胆石病临床流行病学的相关因素.方法 选取胆石病患者2253例作为研究对象,对患者病历资料进行回顾性分析,根据病历情况总结制定胆石病临床流行病学调查情况表进行逐条填写,应用SPSS 13.0进行统计学分析,针对性别、年龄、饮食、职业等相关因素与胆石病的关系进行统计学分析.结果 胆石病病历2253例,其中胆囊结石1937例(85.97%),肝外胆管结石261例(11.58%),肝内胆管结石55例(2.45%).女性高于男性,总比例为1.74:1,性别和各组胆石病部位差异无统计显著意义.41~50岁和51~60岁两区组为胆石病发病年龄高峰,2组之和高达51.04%,差异有统计学意义(P<0.05).胆囊结石患者的饮食结构中高脂饮食高达86.9%,肝内胆管结石患者饮食结构中高脂饮食比例较低,约为1.02%,主要饮食集中于蛋白质饮食(17.2%)和糖类(27.4%);肝外胆管结石患者饮食结构中蛋白质饮食比例较大,高达37.5%.农民发病率最高(38.6%),其次为职员(35.9%).结论 本地区胆石病主要类型为胆囊结石,发病年龄主要集中在40~60岁之间,性别、饮食和职业与胆石病发病存在密切的关联.