异丙酚和异氟醚麻醉对老年患者术后认知功能的影响分析

摘要

ObjectiveTo investigate the propofol and isoflurane anesthesia effects on cognitive function after surgery for elderly patients. Methods38 patients were randomly selected to surgical treatment of elderly patients as observation group, give propofol anesthesia; Another choose 38 cases as control group, give isolfurane anesthesia, compared two groups of elderly patients with cognitive function after using different drug anesthesia in the operation.ResultsThe observation group of patients before anesthesia and postoperative 6 h, 12 h, 24 h MMSE score (27.68 ± 2.08), respectively (23.18±2.26), (25.74±1.65), (27.92±1.97); control group patients before anesthesia and postoperative 6 h, 12 h, 24 h MMSE score (27.77±1.99), respectively (20.37±2.01), (21.37±1.54), (26.21±1.27), after the anesthesia of MMSE is significant difference between group (P < 0.05).ConclusionElderly patients with intraoperative use of cognitive dysfunction after propofol anaesthesia recovery faster than isolfurane.%目的：探讨异丙酚与异氟醚麻醉对老年患者术后认知功能的影响。方法随机选取38例需手术治疗的老年患者作观察组，给予异丙酚麻醉；另选取38例作对照组，给予异氟醚麻醉，比较2组老年患者手术中采用不同药物麻醉后的认知功能情况。结果观察组患者麻醉前、术后6h、12 h、24 h MMSE评分分别为（27.68±2.08）、（23.18±2.26）、（25.74±1.65）、（27.92±1.97）；对照组患者麻醉前、术后6 h、12 h、24h MMSE评分分别为（27.77±1.99）、（20.37±2.01）、（21.37±1.54）、（26.21±1.27），麻醉后的MMSE评分组间比较差异有统计学意义(P<0.05）。结论老年患者术中采用异丙酚麻醉术后认知功能障碍恢复较异氟醚快。