粤北山区非酒精性脂肪肝的患病率及相关影响因素分析

摘要

目的 探讨粤北山区非酒精性脂肪肝的患病情况以及影响因素. 方法 随机抽取2013年1月到2014年6月粤北山区10 000份健康体检数据作为研究对象, 计算非酒精性脂肪肝的患病率, 并对其相关影响因素进行单因素分析和多因素回归分析.结果 10 000名受检者中, 非酒精性脂肪肝的检出率为30.34%. 多因素Logistic回归分析显示, 高龄、 男性、 肥胖、 高血糖、 高尿酸血症、 低HDL-C血症、 高TG血症等是影响非酒精性脂肪肝的主要因素. 结论 粤北山区非酒精性脂肪肝的患病率高, 相关因素多. 定期临床检查, 针对性的防治, 改变不良生活习惯, 是降低非酒精性脂肪肝发病率的重要途径.%Objective To explore the prevalence and related factors of nonalcoholic fatty liver in mountain areas of north Guangdong. Methods The clinical data of 10 000 cases of physical examination in mountain areas of north Guangdong from January 2013 to June 2014 were randomly selected as research objects. The prevalence of nonalcoholic fatty liver was calculated, and the univariate and multivariate regression analysis were taken to analyze the related factors of nonalcoholic fatty liver. Results Among 10 000 cases, the detection rate of nonalcoholic fatty liver was 30.34%. Multivariate regression analysis showed that advanced age, male gender, obesity, high blood sugar, high uric acid, low HDL-C levels, and high TG hyperlipidemia were the main influence factors of nonalcoholic fatty liver. Conclusions The prevalence of nonalcoholic fatty liver in mountain areas of north Guangdong is high, with a lot of related factors. Periodic clinical examination, targeted prevention, and changing bad habits are the important ways to reduce the incidence of nonalcoholic fatty liver.