平山病颈部正常位及过屈位的体感诱发电位研究

摘要

Objective The study was to find the difference of somatosensory evoked potential(SEP) with the neck in neutral and flexion positions of Hirayama disease.Methods Upper and lower limb SEP in neck neutral and flexion positions were recorded in four patients with Hirayama disease and four healthy subjects.Results The amplitude of N13 potential in neck flexion position was (2.53±0.74)μV in Hirayama disease and (4.13± 1.12) μV in control group( P <0.01).Incubation period of N13 had significant difference in neck neutral position between two groups (12.56±0.32) ms vs (11.78±0.53) ms( P <0.01).P1 potential latency showed no significant difference between two groups.The P1 potential amplitudes of two groups were as follows;neck neural position: Hirayama disease group (1.33±0.59) μV and the control group (2.73±1.74) μV( F<0.05) sneck flexion position:case group (1.23 ±0.78) μV and control group (2.51 ± 1.52) μV( P <0.05).We found no significant statistical difference in N13 amplitudes of neural position, N13 latency of flexion position and P1 latency in two positions between two groups.Conclusion There may be slight subclinical sense damage in Hirayama disease.%目的 观察平山病患者颈部正常位及过屈位的上下肢体感诱发电位(somatosensory evoked potential,SEP)是否有异常.方法 分别对平山病(平山病组)4例及健康者(正常对照组)4例进行颈部正常位及过屈位时正中神经和胫神经的SEP检测.结果 N13电位在过屈位时波幅在平山病组及正常对照组分别为(2.53±0.74)μV vs(4.13±1.12) μV(P ＜0.01),N13潜伏期在正常位时在两组分别为(12.56±0.32) ms vs (11.78±0.53) ms(P＜0.01).平山病组和正常对照组P1正常位波幅为(1.33±0.59) μV vs (2.73±1.74)μV(P＜0.05)；过屈位波幅为(1.23±0.78)μV vs (2.51±1.52) μV(P ＜0.05).而两组在N13正常位波幅、过屈位潜伏期和P1正常位和过屈位的潜伏期,均未发现差异有统计学意义.结论 平山病患者可出现感觉通路的轻度受损.