127例脑动静脉畸形破裂出血的危险因素分析

摘要

Objective To analyze the relevantly risk factors of cerebral arteriovenous malformation (AVM ) with hemorrhage . Methods The clinical data of 127 patients with cerebral arteriovenous malformation were retrospectively analyzed .71 patients with hemorrhage were divided into the hemorrhage group while 56 patients without hemorrhage were divided into the control group .The clinical data of the two groups were compared and analyzed .Results Univariate analysis indicated that the differences of location and size of the AVM masses ,location of the feeding arteries ,direction of the draining vein ,combining with aneurysms and size of aneurysms were statistically significant (P<0 .05) .When stepwise multiple logistic regression analysis was employed ,deep AVM masses ,small-sized AVM masses(<3 cm) ,deep draining veins and combining with aneurysms were dependent predictors of hemor-rhagic presentation(P<0 .05 ,OR>1) .Conclusion The patients with deep AVM masses ,small-sized AVM masses(<3 cm) ,deep draining veins and combining with aneurysms should be operated as soon as possible to avoid hemorrhage .%目的：探讨分析脑动静脉畸形破裂出血的相关危险因素。方法回顾性分析127例脑动静脉畸形患者的临床资料，破裂出血患者（71例）作为出血组，未发生破裂出血患者（56例）为对照组。对两组患者的临床资料进行因素分析。结果单因素分析显示，出血组与对照组的畸形血管团位置、畸形血管团大小、供血动脉位置、引流静脉的方向、合并动脉瘤及所合并动脉瘤大小比较差异有统计学意义（P＜0．05）；非条件多因素Logistic回归分析结果显示，位于深部的小于3 cm血管团、深部引流静脉、合并动脉瘤与脑血管畸形是破裂出血的危险因素（ P＜0．05，OR＞1）。结论对于深部血管团小于3 cm、深部引流静脉、合并动脉瘤的脑血管畸形患者，应尽早实施手术治疗。