血浆脑钠素和同型半胱氨酸在急性冠状动脉综合征中的临床应用价值

摘要

Objective To explore the clinical application value of plasma brain natriuretic peptide(BNP) level and homocysteine (HCY) in the patients with acute coronary syndrome( ACS). Methods 85 patients with ACS hospitalized in this hospital from December 2009 to April 2011 were selected as the ACS group and contemporaneous 72 individuals of healthy examination as the control group. The plasma level of BNP and HCY were compared between the two groups. Results The plasma level of BNP and HCY in the ACS group was significantly higher than that in the control group(P<0. 05). The plasma levels of BNP and HCY in the ACS group showed positive correlation,the correlation coefficient r=0. 421 ,P<0. 05. Conclusion The plasma level of BNP and HCY is significantly correlated with ACS and can be used as the risk stratification and prognosis evaluation of ACS.%目的 探讨血浆脑钠素(BNP)和同型半胱氨酸(HCY)在急性冠状动脉综合征(ACS)中的临床应用价值.方法 选择2009年12月至2011年4月该院住院的ACS患者85例为ACS组,同期体检健康者72例为对照组,比较两组的血浆BNP和HCY水平.结果 ACS组患者BNP和HCY值均高于对照组(P<0.05),ACS组血浆BNP水平和血浆HCY水平呈正相关,相关系数(r)=0.421.结论 血浆BNP和HCY水平与ACS病情显著相关,可作为ACS的危险分层和预后评估.