比阿培南治疗中性粒细胞减少伴发热的64例恶性血液病患者的疗效观察

摘要

目的 评价比阿培南对中性粒细胞减少伴发热的恶性血液病患者的临床疗效.方法 回顾性分析2011年3月至2012年5月该院住院的中性粒细胞减少伴发热的恶性血液病患者64例的临床资料.结果 有效率为73.4%,细菌学清除率为55.6%,不良反应率为4.7%.结论比阿培南治疗中性粒细胞减少伴发热的恶性血液病患者安全有效.%Objective To evaluate the clinical efficacy of biapenem for treating febrile neutropenia in malignant hematonosis. Methods The clinical data in 64 patients with malignant hematonosis complicated with febrile neutropenia in this hospital from March 2011 to May 2012 were retrospectively analyzed. Results The total clinical effective rate was 73. 4%,the bacterial eradica tion rate was 55. 6% and the adverse reaction rate was 4. 7%. Conclusion Biapenem is safe and effective for treating febrile neu tropenia in the patients with malignant hematonosis.