目的：观察负压伤口治疗（N PW T ）技术不同负压值对植皮效果的影响，探索适宜的负压值。方法选取该院2012年1～7月四肢慢性创面床拟行植皮术的80例患者分为A～H 8组，A组植皮后常规打包加压，B～ H组分别施加－10、－20、－30、－40、－50、－60和－70 kPa的持续负压，并观察效果。结果施加负压的B～H组在患者舒适度、皮片存活面积和伤口愈合时间方面显著优于A组（P＜0．05）。－10～－40 kPa间，舒适度随负压值的增加而降低（P＜0．05）；皮片存活面积在B、C组最大；创面愈合时间B、C组最快（P＜0．05）。结论植皮创面施加－10 kPa压力的持续负压，即可提高植皮效果又能保证患者舒适度。%Objective To study the effect of different negative pressure values of negative pressure wound therapy (NPWT) effect on skin graft .Methods Eighty patients were selected ,who underwent chronic wound bed and preparedto treat with skin graft in surgical ward of emergency department in the Second Affiliated Hospital of Chongqing Medical University from January 2012 to July 2012 .Eighty patients were divided into 8 groups ,group A were treated with packing pressure after skin graft ,group B~ H were treated with continuous NPWT ,pressures were -10 ,-20 ,-30 ,-40 ,-50 ,-60 and -70 kPa ,respectively .Whether they were in comfortable situation at second day after surgery were observed .Flap survival area at Seventh day after surgery was meas‐ured .Results The patient comfort ,flap survival area ,wound healing time of group B to H were higher than those of group A (P<0 .05) .Patient comfort tended to decrease with the increasing negative pressure values between -10 - -40 kPa(P<0 .05) .Flap survival area ,healing time of group B ,C were higher than those of group D to F(P<0 .05) .Conclusion Application of NPWT technology in wound ,-10 kPa negative pressure value can not only improve wound blood circulation ,but also ensure patient be comfortable .
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