老年脊柱结核病灶清除和植骨融合术后复发的危险因素分析

摘要

目的：研究老年脊柱结核病灶清除和植骨融合术后复发的危险因素。方法对2003年1月至2013年12月415例老年脊柱结核患者的资料进行回顾性分析。415例老年脊柱结核患者中46例术后出现复发（观察组），369例术后治愈（对照组）。统计两组受试者术前抗结核治疗时长、手术清除病灶程度、术后规范治疗、骨外结核、耐药、术后制动时长、合并系统性疾病、贫血或营养不良等情况。结果术前抗结核治疗时长、手术清除病灶程度、术后规范治疗、骨外结核、耐药、术后制动时长、合并系统性疾病、贫血或营养不良与老年脊柱结核术后复发密切相关，为其独立危险因素。结论老年脊柱结核病灶清除和植骨融合术后复发与多种因素密切相关。%Objective To study the risk factors of recurrence after debridement bone graft fusion in elderly patients with spi‐nal tuberculosis(TB) .Methods The data of 415 elderly patients with spinal tuberculosis in our hospital from January 2003 to De‐cember 2013 were retrospectively analyzed .Among them ,46 cases (observation group) recurred and 369 cases(control group) had no postoperative recurrence .The preoperative anti‐TB treatment duration ,surgical removal degree of lesions ,postoperative stand‐ardized therapy ,extra‐skeletal TB ,drug resistance ,postoperative braking duration ,complicating systemic disease ,anemia or malnu‐trition ,etc .were statistically analyzed .Results Preoperative anti‐TB treatment duration ,surgical removal degree of lesions ,postop‐erative standardized therapy ,extra‐skeletal TB ,drug resistance ,postoperative braking duration ,complicating systemic disease ,ane‐mia or malnutrition were the major risk factors for postoperative recurrence of senile spinal TB ;preoperative anti‐TB treatment du‐ration ,surgical removal degree of lesions ,postoperative standardized therapy ,extra‐skeletal TB ,drug resistance ,postoperative bra‐king duration ,complicating systemic disease and anemia or malnutrition were closely related with postoperative recurrence of senile spinal TB ,which were their independent risk factors .Conclusion The recurrence of senile spinal tuberculosis and bone graft fusion and is closely related to various factors .