2015-2016年吉林大学第一医院儿科急诊清热解毒类中药注射液使用情况分析及合理性评价

摘要

目的:分析吉林大学第一医院儿科急诊清热解毒类中药注射液的使用情况及用药趋势,为临床合理用药提供参考.方法:利用医院HIS系统调取我院儿科急诊2015-2016年的门诊处方,筛选含清热解毒类中药注射液的处方,对品种、金额、用药频度(DDDs)等进行统计,并对年龄、临床诊断、联合用药等药品使用情况做回顾性分析;利用PASS合理用药系统,评价清热解毒类中药注射液处方用药的合理性.结果:2015-2016年我院儿科急诊清热解毒类中药注射液用药金额分别为人民币367362. 7元、 475579. 58元,占全年药品销售总额的8. 93％、4. 35％;主要使用品种为热毒宁注射液、痰热清注射液和喜炎平注射液3种.2015年热毒宁注射液的年销售额居首位.喜炎平注射液的DDDs由2015的805. 56增至2016年的1685. 28,超过热毒宁注射液跃居首位;不合理用药方面存在用法用量不适宜、适应证不适宜、超说明书用药、联合用药不适宜等情况.结论:我院儿科急诊清热解毒类中药注射液的使用基本合理,但也有不合理之处,可以通过药师干预、处方点评等方法改进.%Objective: To Analyze the usage and medication trend of antipyretic and detoxifying traditional Chinese medicine injection in pediatric emergency room of our hospital and to provide references for rational drug use. Methods: Hospital HIS system was used to retrieve outpatient prescriptions from 2015 to 2016 in pediatric emergency room of our hospital and the prescriptions containing antipyretic and detoxifying traditional Chinese medicine injection were selected. The varieties, amount of money and DDDs were analyzed. Furthermore, ages, clinical diagnosis, combined medication and other aspects were retrospectively analyzed. The rationality of prescriptions containing antipyretic and detoxifying traditional Chinese medicine injection was evaluated by using the PASS rational drug use system. Results: The amount of the antipyretic and detoxifying traditional Chinese medicine injection in our hospital in 2015 and 2016 was 197362. 7 yuan and 475579. 58 yuan respectively, accounting for 8. 93％ and 4. 35％ of the total sale amount of medicines. The top 3 varieties used were Reduning Injection, Tanreqing Injection and Xiyanping Injection. The annual sale amount of Reduning Injection ranked the first place in 2015. DDDs of Xiyanpin Injection increased from 805. 56 in 2015 to 1685. 28 in 2016, which surpassed Reduning Injection and ranked the first place. Irrational use of antipyretic and detoxifying injection of traditional Chinese medicine consisted of inappropriate usage and dosage, inappropriate indication, off-lable medication, inappropriate drug combination, and so on. Conclusion: The usage of antipyretic and detoxifying traditional Chinese medicine injection in pediatric emergency room of our hospital was basically reasonable, however, there were unreasonable aspects which can be improved by means of pharmacist intervention, prescription review and other methods.