APPLICATION OF VACCINIUM AXILLARE NAKAI SHOOTS AS MEDICATION, DEMONSTRATING ACTIVISATION OF GLUCOSE UTILISATION BY BRAIN IN TREATMENT OF DIABETES MELLITUS

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention relates to pharmacology and is intended for extension of nomenclature of herbal medications for treatment of diabetes mellitus (DM). Studied are properties of Vaccinium axillare Nakai shoots, Far East plant, which had not been studied before. Glucose-tolerant test, made on male rats of Wistar line with weight 200-220 g, showed reliable hypoglycemic and glucosuric action of Vaccinium axillare Nakai shoots. Hypoglycemic effect of Vaccinium axillare Nakai is also confirmed in experiment on alloxan diabetes model. It has been established that newly studied plant activates glucose utilisation by brain, aggravated by angiopathy, at the background of alloxan diabetes.;EFFECT: obtained results indicate that Vaccinium axillare Nakai shoots have hypoglycemic and glucosuric effect and that new object has advantage in comparison with Vaccinium myrtillus due to more expressed hypoglycemic action and ability to activate glucose utilisation by brain in case of DM.;1 tbl