2例颅内青少年黄色肉芽肿的影像学表现分析

摘要

Objective To explore the relationship between the radiological characteristics and clinical and pathological manifestations of intracranial juvenile xanthogranuloma. Methods The radiological and clinical characteristics of two intracranial juvenile xanthogranuloma cases were analyzed respectively. In combination with reviewing literatures, the radiological characteristics and discipline of intracranial juvenile xanthogranuloma disease were also analyzed. Results Intracranial juvenile xanthogranuloma disease was accidently detected in one case. The other case was detected with headache and numbness in face. No abnormal sign was found in skin. On plain CT isodensity signals appeared and on contrast-enhanced CT homogeneous enhancement was found.On MR imaging,masses showed isointense signals on T1WI and iso-or hypo-intensity signals on T2WI, and enhanced homogeneously. Lesions were solitary or multiple in the external of brain. After operation intracranial juvenile xanthogranuloma was confirmed by pathology, and no recurrence occurred. Conclusion Intracranial juvenile xanthogranuloma is a kind of rarely encountered disease with typically radiological characteristics, which is difficult to detect before surgery and can be confirmed by post-operative pathological and immunohistochemical examinations.[Chinese Medical Equipment Journal,2018,39(5):71-74]%目的:探讨颅内青少年黄色肉芽肿的影像学表现以及与临床、病理之间的联系.方法:回顾性分析2例发生于颅内的青少年黄色肉芽肿病例的临床及影像学资料,并总结文献报道,分析该病在颅内的影像学征象及规律.结果:1例患者偶然发现,1例患者有头疼及脸部麻木表现,2例皮肤均无异常反应.影像学表现CT平扫为等密度,增强扫描明显均匀强化;MRI T1WI呈等信号,T2WI信号不均匀,等信号为主或呈均匀稍低信号,增强扫描明显强化.病变单发或多发,无脑膜尾征及瘤周血管,病灶位于脑外,术后病理证实为青少年黄色肉芽肿,术后无复发.结论:颅内青少年黄色肉芽肿非常罕见,影像学表现有一定特征,术前诊断困难,确诊需术后病理及免疫组化验查.