绵阳市1963～1997年钩端螺旋体病疫情及流行菌株变化分析

摘要

The article analyzed the change of Leptospirosis and strain of Leptospira interrogans in Mianyang in 1963-1997. The annual average incidencd rate is 4. 73 and the mortality rate is 0. 079 per one hundred thousand persons. In this area,the distribution of Leptospirosis agreed on others internal reports in sex ,age,profession and seasonlity. 5 outbreaks have been taken place in 35 years. Four of which were major Icterohaemorrhagiae serogroup Icterohaemorrhagiae sertoype and one was Hebdomadis Serogroup Hebdomadis Serotype. Leptospira 7 Serogroup and 10serotype have been found in 49 Leptospira interrogans which have been cultivated from blood of patients. It supports that rodent is the principal infections source of Leptospirosis that 174 Leptospira interrogans have been isolated from rodent.%本文报告了四川绵阳市35年钩端螺旋体病(下称钩体)疫情及流行菌株情况，年平均发病率4.73／10万，年平均死亡率0.079／10万，钩体病的性别、年龄、职业及季节分布与国内报道相一致。35年中发生5次局部暴发流行，4次以黄疽出血型为主，一次以七日热型为主。从病人血分离到49株钩体菌，分属七群10个血清型，从动物体内分离到菌株174株，证实啮齿类动物为主要传染源。