目的 探讨室间隔缺损致艾森曼格综合征患者妊娠的危险性及应对措施.方法 回顾分析2例妊娠合并室间隔缺损致艾森曼格综合征患者的诊疗经过.结果 1例患者因合并上呼吸道感染、妊娠期高血压疾病,于孕36+4周剖宫产终止妊娠,术后12天拆线,术后13天顺利出院.1例患者因先兆早产入院,于孕36+3周剖宫产终止妊娠,术后5天因持续性肺动脉高压、低氧血症致呼吸循环衰竭而死亡.结论 室间隔缺损演变为重度肺动脉高压、艾森曼格综合征的患者不宜妊娠,一旦妊娠应在早孕阶段终止.对于坚持妊娠者应加强孕期管理,择期剖宫产终止妊娠并加强围手术期监护.%Objective To analyze the risk and countermeasures of pregnancy in women suffering eisenmenger syndrome induced by ventricular septal defect. Methods The diagnosis and treatment of 2 patients with eisenmenger syndrome induced by pregnancy complicating ventricular septal defect were analyzed retrospectively. Results Cesarean section was performed at 36+4 week on one case in pregnancy complicating upper respiratory tract infection and hypertensive disorder complicating pregnancy. Stitch was removed at 12th day and the patient was discharged at 13th day after cesarean section. Another case was admitted for threatened preterm labor and performed at 36+3 week to cease pregnancy. Five days after operation, the patient died because of respiratory and circulatory failure caused by persistent pulmonary hypertension and hypoxemia. Conclusion Patients with ventricular septal defect inducing severe pulmonary hypertension and eisenmenger syndrome should not be pregnant. Pregnancy should be terminated at early stage. For patients insisting on pregnancy, close observation should be provided, pregnancy should be terminated with selective cesarean section and perioperative monitoring should be strengthened.
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