背景：有研究认为高黏度骨水泥可以减少经皮椎体成形治疗中的骨水泥渗漏，但相比低黏度骨水泥是否具有临床优势，目前还存在争论。目的：比较经皮椎体成形治疗中使用高黏度骨水泥或低黏度骨水泥治疗骨质疏松性椎体压缩骨折的骨水泥渗漏率和临床疗效。方法：将60例骨质疏松性椎体压缩骨折行经皮椎体成形治疗患者随机抽签分为两组，分别采用高黏度骨水泥与低黏度骨水泥修复，比较两组患者骨水泥静脉渗漏率、椎间盘渗漏率、腰痛目测类比评分及Oswestry功能障碍指数。结果与结论：所有患者均顺利完成手术，两组末次随访腰痛目测类比评分和Oswestry功能障碍指数均明显低于治疗前(P=0)；两组间末次随访腰痛目测类比评分、Oswestry 功能障碍指数及骨水泥椎间盘渗漏率差异无显著性意义；高黏度骨水泥组骨水泥静脉渗漏率低于低黏度骨水泥组(P=0)。提示经皮椎体成形治疗中使用高黏度骨水泥可降低骨水泥渗漏。%BACKGROUND:Studies have suggested that high-viscosity bone cement can reduce bone cement leakage in the percutaneous vertebroplasty, but compared to the low-viscosity bone cement, there are stil some controversies on clinical advantages of high-viscosity bone cement. OBJECTIVE:To compare the bone cement leakage and clinical outcomes of high-viscosity and low-viscosity bone cement in percutaneous vertebroplasty for osteoporotic vertebral fractures. METHODS:Sixty patients with osteoporotic vertebral fractures were enroled in this study. Al patients were randomly divided into two groups: high-viscosity bone cement group and low-viscosity bone cement group. We compared the venous leakage rate, disc leak rate, visual analogue scale scores for low back pain, and Oswestry disability index between two groups. RESULTS AND CONCLUSION:Al patients were successfuly operated and low back pain and Oswestry disability index had significant improvement as compared with the preoperative status (P=0). By the final folow-up visit, there was no significant difference in disc leak rate, visual analogue scale scores, and Oswestry disability index between two groups. The venous leakage rate in the high-viscosity bone cement group was lower than that in the low-viscosity bone cement group (P=0). This study shows that high-viscosity bone cement can reduce bone cement leakage in the percutaneous vertebroplasty.
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