A calcium channel blocker, gallopamil hydrochloride, was synthesized from 2-(3,4,5-tri-methoxyphenyl) acetonitrile and 2-(3,4-dimethoxyphenyl)-N-methylethylamine by nucleophilic substitution and salt forming reaction. The structure was characterized by 1H NMR and MS.%以2-(3,4,5-三甲氧基苯基)乙腈和2-(3,4-二甲氧基苯基)-N-甲基乙胺为起始原料,经亲核取代反应和成盐反应合成了一种钙通道阻滞剂——盐酸戈洛帕米,其结构经1H NMR和MS确证.
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