侵犯胸壁T3N0-1M0期NSCLC术后辅助放疗进展

摘要

肺癌是目前全球最常见的恶性肿瘤,对于局部晚期NSCLC其2年LC率只有20％～40％,故降低LR率,提高OS成为重要研究目标,但对侵及胸壁的早期肺癌术后辅助治疗有一定争议.我们从胸壁解剖学特点、手术方式、失败模式及术后放疗等方面回顾了侵犯胸壁T3 N0-1M0期的NSCLC研究现状.%Currently,lung cancer is the most common malignant tumor in the world.The local control (LC) rate is only 20％-40％ for patients with local advanced non-small cell lung cancer (NSCLC).Hence,reducing the LC rate and enhancing the overall survival (OS) are pivotal research objectives.However,postoperative adjuvant treatment for patients with early NSCLC with chest wall invasion is still controversial.In this article,the research progress on T3 N0-1M0 NSCLC with chest wall invasion was reviewed from the perspectives including anatomical features,types of resection,patterns of failure and postoperative radiotherapy,etc.