Objective To investigate the relationship between fibrinogen ,D-dimer and short term prognosis in patients with venous sinus thrombosis (CVST ). Methods Fifty-six cases of CVST patients admitted to the hospital were selected as CVST group ,plasma fibrinogen and D-dimer were detected and 50 cases of healthy people were selected as control group. Ac-cording to the modified Rankin Scale (MRS) score ,CVST were subdivided into good prognosis group and poor prognosis group ,and fibrinogen and D-dimer of two groups were compared. Results D-D ,FBG in venous sinus thrombosis patients was respective (316.37 ± 14.59) ng/mL ,(4.96 ± 1.27) g/L ,which was significantly higher than those of control group ;D-D ,FBG in good prognosis group was respective (289.34 ± 22.37 ) ng/mL ,(4.58 ± 1.16) g/L ,which was significantly lower than CVST group with a poor prognosis. Conclusion Plasma fibrinogen and D-dimer have important clinical value for diagnosis and prognosis of CVST patients .%目的：探讨静脉窦血栓形成（CVST ）患者纤维蛋白原、D-二聚体与短期预后的关系。方法选取 CVST 患者56例为 CVST 组，检测血浆纤维蛋白原、D-二聚体，并与50例健康者（对照组）作对照。按改良 Rankin 量表（mRS）评分，将CVST 患者再分为预后良好组和预后不良组，并对比2组纤维蛋白原、D-二聚体水平。结果静脉窦血栓形成患者组 D-D 、Fbg 分别为（316.37±14.59）ng／mL 、（4.96±1.27）g／L ，均显著高于对照组；预后良好组 D-D 、Fbg 分别为（289.34±22.37） ng／mL 、（4.58±1.16）g／L ，均显著低于 CVST 预后不良组。结论血浆纤维蛋白原、D-二聚体对于 CVST 的诊断和短期预后判断有重要临床价值。
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