睾丸生殖细胞瘤临床特点及诊治分析:附45例报告

摘要

Objective To investigate the diagnosis and therapy of testicular germ cell tumour.Methods The clinical data of 45 cases that were confirmed by pathology testicular germ cell tumour were retrospectively analyzed.Results All 45 cases were resected successfully.Among of them,28 cases seminoma,3 cases teratoma,2 cases embryoma,2 cases choriocarcinoma,4 cases mixed testicular germ cell tumour,5 cases yolk sac tumor,1 case spermatocytic seminoma.The treatment method was selected by pathology results.Eleven cases were lost,34 cases were followed up for 3 month to 5 years,25 cases seminoma,9 cases non-seminoma,5 cases were died.Conclusion Surgical resection and adjuvant chemotherapy are important factors for testicula disease.%目的 探讨睾丸生殖细胞瘤的诊断及治疗.方法 回顾性分析45例经手术病理证实为原发睾丸生殖细胞瘤患者的临床资料.结果 45例均行手术治疗,术后病理检查示精原细胞瘤28例,畸胎瘤3例,胚胎癌2例,绒毛膜上皮癌2例,混合性生殖细胞瘤4例,卵黄囊瘤5例,精母细胞型精原细胞瘤1例.根据术后病理结果选择相应放化疗方案.术后随访3个月至5年,11例失访,34例获得随访,精原细胞瘤25例,非精原细胞瘤9例,死亡5例.结论 怀疑睾丸病变者早期手术治疗及辅助行放化疗是提高临床治愈的关键.