Flap is a main way to repair complex wound defects,however its related complications cannot be ignored.The wound negative pressure therapy (NPWT) can help to promote angiogenesis and granulation,absorb tissue exudate,inhibit bacterial proliferation.It also help with flap survival,savingcrisis flaps,and accelerating wound healing of donor site.Therefore,the NPWT is widely used in tissue repairment and reconstruction.This article reviewed and summarized the mechanism of NPWT,as well as its application in the donor and recipient site of flap.%皮瓣是修复复杂创面缺损的主要方式,其相关并发症引发的问题不容忽视.创面负压治疗技术具有促血管生成、促肉芽形成、抽吸多余组织渗出液、抑制细菌增殖等作用,在促皮瓣成活、挽救危象皮瓣、促皮瓣供区愈合方面有积极疗效,在修复重建领域中得到广泛应用.作者对创面负压治疗技术的机制及其应用于皮瓣供区和受区的积极意义进行了综述.
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