注射用质子泵抑制剂不合理用药典型实例分析

摘要

Objective To investigate and analyze the medication rationality of injective proton pump inhibitors (PPIs) for inpatients in a third class general hospital,so as to promote rational application of injective PPIs.Methods A random 200 medical records of using injective PPIs in hospitalized patients in 2014 were statistical analyzed, including patients’gender, age, department, indication, drug variety, dosage, course of treatment, and commented irrational medication examples.Results Injective PPIs are widely used in clinic, there is a certain of unreasonable medication in parts of medical records, including drug unreasonable selection, no indication of drug use and longer courses, etc.Conclusion Injective PPIs medication standards should be formulated by hospital, and the use of injective PPIs should be strictly controlled in clinic, avoiding excessive and irrational use of PPIs, reducing the cost of drugs and adverse drug reactions.%目的对某三级综合医院住院患者注射用质子泵抑制剂(proton pump inhibitors, PPIs)临床应用的合理性进行调查分析,为临床合理用药提供参考。方法随机抽查2014年度200名使用注射用PPIs 的住院患者病历,对患者性别、年龄、住院科室、适应证、用药品种、剂量、用药时间等进行统计分析,并对不合理用药实例进行评价。结果注射用PPIs 临床使用广泛,在一定程度上存在着用药选择不合理、无明确用药指征和使用时间偏长等问题。结论医院应制定注射用PPIs 临床使用规范,临床使用中应严格把握用药指征,避免注射用PPIs不规范使用和过度使用,降低患者药品费用,减少药品不良反应。