首页> 中文期刊> 《中华老年多器官疾病杂志》 >蒽环类抗肿瘤药诱发心肌病1例及文献复习

蒽环类抗肿瘤药诱发心肌病1例及文献复习

         

摘要

回顾性分析1例病情特殊的扩张性心肌病患者,65岁女性,之前无心脏病史。主要表现为胸闷、气短,相关检查提示扩张性心肌病,既往因乳腺癌接受蒽环类抗肿瘤药治疗。回顾之前发表的其他病例数据,总结蒽环类抗肿瘤药诱导心肌病的相关诊治经验,采用规范化、个体化治疗后患者症状缓解。因此,应用蒽环类抗肿瘤药治疗时应监测、防治由化疗药物导致的心脏毒性。若病变发展为慢性心脏毒性表现,则尽早应用改善心肌预后的药物。%We retrospectively analyzed a particular case of dilated cardiomyopathy , that is,a 65-year-old woman who had no history of heart disease mainly presenting chest tightness and shortness of breath .Related examinations suggested dilated cardiomyopathy , and the patient had ever received anthracycline drugs for breast cancer treatment .We reviewed related literatures and summarized the experience on diagnosis and treatment of anthracycline-induced cardiomyopathy .After standardized and individualized treatment , her symptoms were relieved .Therefore , we should monitor cardiac function during anthracyclines administration to prevent and treat cardiac toxicity caused by chemotherapy drugs .If the condition developes into chronic heart disease , the drugs to improve myocardial prognosis should be used as early as possible .

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