超声造影和增强CT诊断胰腺局灶性病变的Meta分析

摘要

Objective To utilize Meta-analysis in estimating the diagnostic value of contrast enhanced ultrasound CCEUS) and contrast enhanced computed tomography (CECT) for benign and malignant focal pancreas lesions. Methods English and Chinese articles related to CEUS and CECT diagnosis and differential diagnosis of benign and malignant focal pancreas lesions in PubMed and CNKI database were evaluated and selected. The included data were analyzed with Meta-disc 1. 4 software. Results Fourteen studies were included. The pooled sensitivity, specificity and the area under curve (AUC) of summary receiver operating characteristic (SROC) curve in CEUS and CECT was 89.20%, 94.00%, 0.9545 and 85. 50% , 84. 60% , 0. 9116, respectively. The accuracy of CEUS in diagnosis of focal pancreas lesions was higher than that of CECT (P< 0.005). Conclusion For focal pancreas lesions, CEUS is a noninvasive inspection method with high accuracy.%目的 运用Meta分析评价超声造影(CEUS)和增强CT(CECT)对良、恶性胰腺局灶性病变的诊断价值.方法 对PubMed、中国期刊网CNKI数据库有关CEUS及CECT诊断及鉴别诊断良、恶性胰腺局灶性病变的中英文文献进行评价和筛选,同时应用Meta-disc 1.4软件对入选文献的试验数据进行分析.结果 14篇文献符合纳入标准.CEUS与CECT诊断良、恶性胰腺局灶性病变的合并敏感度、特异度、SROC曲线下面积(AUC)分别为89.20％、94.00％、0.9545和85.50％、84.60％、0.9116.CEUS与CECT诊断良、恶性胰腺局灶性病变的准确率差异有统计学意义(P＜0.005).结论 对于胰腺局灶性病变,CEUS是一种准确性较高的无创性检查方法.