实时三维超声心动图容积-时间曲线评价扩张型心肌病患者左心室收缩及舒张早期同步性

摘要

Objective To evaluate the left ventricular systolic and early diastolic synchrony in patients with dilated cardiomyopathy (DCM) using real time three-dimensional echocardiography (RT-SDE) volume-time curves (VTC). Methods Thirty-seven patients with DCM (DCM group) and 27 healthy subjects (control group) were examined with RT-3DE. VTC of two groups were analyzed. Standard deviation of time to minimal systolic volume (Tmsv-SD), and standard deviation of time to early diastolic volume (Tedv-SD) about 16, 12, 6 segments were obtained and standardized using R-R interval as systolic dyssynchrony index (SDI) and early diastolic dyssynchrony index (DDI). Results ①Compared with those of the control group, SDI and DDI were higher in DCM group. ② SDI and DDI had negative correlation with LVEF in DCM group. Conclusion There was left ventricular systolic and early diastolic dysynchrony in patients with dilated cardiomyopathy.%目的 应用实时三维超声心动图(RT-3DE)容积-时间曲线(VTC)评价扩张型心肌病(DCM)患者左心室收缩期及舒张早期同步性.方法 对37例DCM患者(DCM组)和27名正常人(对照组)行RT-3DE检查,分析其VTC,得出左心室16节段、12节段、6节段心肌收缩期最小容积达峰时间标准差(Tmsv-SD)及舒张早期容积的时间标准差(Tedv-SD),用R-R间期标准化后,作为收缩期不同步化指数(SDI)、舒张早期不同步化指数(DDI).结果①与对照组比较,DCM组左心室收缩期及舒张早期不同步化指数差异均有统计学意义.②在DCM组中,心肌收缩期SDI及舒张早期DDI均与左心室射血分数(LVEF)呈负相关.结论 DCM患者左心室既存在收缩不同步,也存在舒张早期不同步.