Objective To analyze the clinical, X-ray, MRI, and pathology manifestations of femur diaphysial osteosarco-ma. Methods Thirteen patients with femur diaphysial osteosarcomas were confirmed with pathology. All the patients received X-ray examination, and 9 of them underwent plain and enhanced MR scan. Results Clinical manifestations: Median age of the patients was 15 years. Thigh pain and movement disorders were main clinical symptoms. X-ray and MRI appearances: All of the 13 patients had bone destruction (osteogenic destruction in 11 and osteolytic destruction in 2) and soft tissue mass in 13, periosteal reaction was found in 12 patients, neoplastic bone and tumor calcification in 11 patients. Pathology: In 13 patients of femur diaphysial osteosarcoma, 11 patients were with conventional central osteosarcoma, 1 with small cell osteosarcoma and 1 with low-grade central osteosarcoma. Conclusion Comprehensive analysis of the clinical manifestations, X-ray, MRI appearances and pathology is of significant value in diagnosis of femur diaphysial osteosarcoma.%目的 分析股骨干骨肉瘤的临床、X线、MRI及病理表现.方法 对经手术病理证实的13例股骨干骨肉瘤患者行X线检查,对其中9例行MR平扫及增强扫描.结果 临床表现:中位年龄15岁,临床症状均以大腿疼痛和肢体功能障碍为主.X线和MRI表现:骨质破坏13例(成骨性11例,溶骨性2例),骨膜反应12例,软组织肿块13例,肿瘤骨和瘤样钙化11例.病理表现:骨肉瘤13例中,普通中心型骨肉瘤11例,小细胞型及低级别中心型骨肉瘤各1例.结论 综合分析股骨干骨肉瘤的临床、X线、MRI及病理表现,对临床诊断具有重要意义.
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